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Senior Principal, ML/AI

Xometry

Denver, Co · hybrid · full time · Principal

$150,000 - $196,000

Role Overview

Xometry is seeking a Senior Principal, Machine Learning & Artificial Intelligence to join our team. You will serve as a technical leader for large, cross-functional ML/AI initiatives that have significant and lasting business impact. You will own and drive an 18- to 24-month technical roadmap that balances innovation with business value delivery, working closely with engineering, product, design, manufacturing operations, and business leadership.

How You’ll Contribute

  • Serve as the technical leader of multiple large, cross-functional ML/AI solutions with significant, lasting impact across Xometry’s business.
  • Define and drive the 18-24-month ML/AI technical roadmap, balancing breakthrough innovation (e.g., generative 3D, foundation models, large-scale vision/3D pipelines) with reliable business value delivery (e.g., quoting accuracy, lead-time reduction, defect detection, cost optimization).
  • Influence partner roadmaps across engineering, product, operations, and business teams: align priorities, advise on resourcing, champion ML/AI best practices.
  • Proactively identify and remove roadblocks for teams and projects — whether technical, operational, data-related, or resource constraints.
  • Provide mentorship to individuals and technical teams.
  • Act as a trusted SME shaping ML/AI infrastructure, data, model, and tooling decisions.
  • Play a leadership role in identifying opportunities to use ML/AI to unlock revenue, reduce cost, or optimize efficiency.
  • Address problems adjacent to your sphere of immediate influence and champion holistic solutions.
  • Stay ahead of industry developments in ML, AI, generative AI, 2D/3D modeling, and manufacturing tech.
  • Consistently identify opportunities for incremental growth and efficiency optimization across latency, retraining, compute costs, and automation.

Qualifications

  • Master’s or PhD in Computer Science, Machine Learning, Applied Mathematics, Electrical Engineering, or related field (PhD preferred for deep generative/3D modeling emphasis).
  • 12+ years of professional experience in machine learning, artificial intelligence, or data science roles, with several years in a senior or principal capacity leading major programs.
  • Demonstrated experience architecting and delivering large-scale ML/AI solutions end-to-end (data ingestion, feature engineering, model training, evaluation, deployment, monitoring & operations).
  • Deep expertise in machine learning frameworks (TensorFlow, PyTorch), data engineering, model infrastructure, MLOps, cloud platforms (AWS, GCP, Azure), and scalable production systems.
  • Experience in 3D modeling / geometry / computer vision / generative models (e.g., point-cloud processing, mesh processing, text23D, image23D, CAD/CAM integration) is highly desirable.
  • Strong exposure to generative AI techniques (large language models, multimodal models, diffusion, GANs) and translating them into business use-cases.
  • Excellent cross-functional collaboration and communication skills; ability to influence without direct authority.
  • Track record of identifying and delivering measurable business impact via ML/AI.

Benefits

Competitive benefits package including 401(k) match, medical, dental, and vision insurance, life and disability insurance, paid time off, holidays, parental leave, and EAP.